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Updated: Jul 24, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Explainable online health information truthfulness in Consumer Health Search
Rishabh Upadhyay1, Petr Knoth2, Gabriella Pasi1
1Information and Knowledge Representation, Retrieval, and Reasoning (IKR3) Lab, Department of Informatics, Systems, and Communication, University of Milano-Bicocca, Milan, Italy.
This study introduces a new approach to evaluating online health information, moving beyond simple true/false labels. The enhanced system provides explainable results, improving user trust and understanding of health information accuracy.
Area of Science:
- Information Science
- Health Informatics
- Computer Science
Background:
- Online health information significantly impacts public health decisions.
- Current systems often use binary classification (true/false) for health information, lacking interpretability.
- Existing methods present opaque results, hindering user trust and decision-making.
Purpose of the Study:
- To develop a novel system for assessing the truthfulness of online health information.
- To address the limitations of binary classification and opaque results in current health information assessment tools.
- To enhance the interpretability of health information retrieval for consumers.
Main Methods:
- The study reframes health information assessment as an ad hoc retrieval task, not a classification task.
- An Information Retrieval model incorporating truthfulness as a relevance dimension was extended.
- Explainability was achieved by integrating a knowledge base of scientific evidence from medical journals.
Main Results:
- The proposed solution was evaluated quantitatively and qualitatively through a user study.
- Results demonstrated the system's effectiveness in providing interpretable ranked lists of documents.
- The system improved user understanding of both topical relevance and truthfulness of health information.
Conclusions:
- The novel approach enhances the interpretability of online health information for consumers.
- The explainable retrieval system aids users in making more informed health decisions.
- This work contributes to more trustworthy and transparent online health information access.
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