Stereotactic Therapies for Meningiomas.
Constantin Tuleasca1,2,3,4, Daniel Ruess5, Maximilian Ruge5
1Clinical Neurosurgery Service, Centre Hospitalier Universitaire de Lille, Roger Salengro Hospital, Lille, France.
Advances in Experimental Medicine and Biology
|July 11, 2023
Summary
Stereotactic radiosurgery is an increasingly common first-line treatment for select meningiomas, offering local control rates similar to surgery. This chapter introduces various stereotactic techniques for meningioma treatment.
Area of Science:
- Neurosurgery
- Radiation Oncology
Background:
- Surgery is the primary treatment for most meningiomas.
- Stereotactic radiosurgery is emerging as a viable first-line therapy for specific meningioma cases, especially small tumors in difficult locations.
Purpose of the Study:
- To introduce stereotactic techniques for meningioma treatment.
- To highlight the role of radiosurgery as an alternative to surgery for select meningiomas.
Main Methods:
- Discussion of stereotactic radiosurgery using Gamma Knife.
- Overview of Linear Accelerator-based techniques (CyberKnife, modified LINAC).
- Introduction to stereotactically guided brachytherapy using radioactive seeds.
Main Results:
- Stereotactic radiosurgery demonstrates local control rates comparable to surgical intervention for certain meningiomas.
- Radiosurgery is effective for small meningiomas in challenging or high-risk anatomical areas.
Conclusions:
- Stereotactic radiosurgery is a valuable and increasingly utilized treatment modality for specific meningioma presentations.
- A range of stereotactic techniques are available for meningioma management, offering alternatives to traditional surgery.


