Related Experiment Video
Updated: Jul 23, 2025

Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres
Published on: January 29, 2018
The Epigenetic Landscape of Meningiomas
Justin Z Wang1, Farshad Nassiri2, Kenneth Aldape3
1Division of Neurosurgery, Department of Surgery, The University of Toronto, Toronto, ON, Canada.
Abstract:
Epigenetic changes have been found to be increasingly important in tumor development and progression. These alterations can be present in tumors such as meningiomas in the absence of any gene mutations and alter gene expression without affecting the sequence of the DNA itself. Some examples of these alterations that have been studied in meningiomas include DNA methylation, microRNA interaction, histone packaging, and chromatin restructuring. In this chapter we will describe in detail each of these mechanisms of epigenetic modification in meningiomas and their prognostic significance.
More Related Videos
10:58Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
Published on: February 22, 2015
05:45Quantitative Immunohistochemistry of the Cellular Microenvironment in Patient Glioblastoma Resections
Published on: July 31, 2017
Related Concept Videos
Epigenetic Regulation
X-chromosome...
The Tumor Microenvironment
Genomic Imprinting and Inheritance
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...