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Updated: Jul 19, 2025

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
Published on: August 6, 2019
Minimally Invasive Transforaminal Interbody Fusion Versus Microdiscectomy Without Fusion for Recurrent Lumbar Disk
Salvatore D'Oria1, David Giraldi, Domenico Murrone
1From the Neurosurgical Unit, Miulli Hospital, Acquaviva delle Fonti, Italy (D'Oria, Giraldi, Murrone, Salamone, Tomatis, and Fanelli), and the Department of Neurosurgery, (Dr. Colamaria, Dr. Carbone) "Riuniti" Hospital, Foggia, Italy (Colamaria and Carbone), and the Department of Neurosurgery, University of Catania (Rossitto).
Minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) is more effective than standard revision diskectomy for recurrent lumbar disk herniation. MIS TLIF reduces complications and lower back pain, offering a better outcome for patients needing redo surgery.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Spinal Surgery
Background:
- Recurrent lumbar disk herniation (RLDH) is a common complication following initial microdiscectomy, often necessitating revision surgery.
- Current management strategies for RLDH lack definitive evidence, with options including repeat microdiscectomy or fusion.
- This study addresses the need for comparative data on surgical interventions for RLDH.
Purpose of the Study:
- To compare the clinical outcomes of minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) versus standard revision diskectomy for RLDH.
- To evaluate the efficacy and safety of MIS TLIF as a revision procedure for recurrent lumbar disc herniation.
Main Methods:
- A prospective, randomized, multicenter, comparative study involving 90 patients with RLDH.
- Patients were divided into two groups: standard revision microdiscectomy (n=45) and revision microdiscectomy with MIS TLIF (n=45).
- Outcomes assessed included Japanese Orthopaedic Association scores, operating time, blood loss, hospital stay, costs, complications, and pain using visual analog scale.
Main Results:
- No significant difference in postoperative Japanese Orthopaedic Association scores between groups.
- Postoperative lower back pain was significantly lower in the MIS TLIF group compared to the standard revision group.
- The MIS TLIF group demonstrated lower rates of dural rupture, postoperative neurological impairment, and need for additional revision surgery.
Conclusions:
- Revision microdiscectomy is an effective treatment for RLDH.
- MIS TLIF offers advantages over conventional microdiscectomy for RLDH, including reduced intraoperative risks and improved postoperative outcomes regarding pain and stability.
- MIS TLIF is recommended for managing RLDH to minimize complications and enhance patient recovery.

