Local Methotrexate Plus Uterine Artery Embolization for High-Risk Interstitial Ectopic Pregnancy

Area of Science:

• Reproductive Medicine
• Minimally Invasive Gynecologic Surgery
• Maternal-Fetal Medicine

Background:

• Interstitial ectopic pregnancy is a rare and life-threatening condition with high risks of rupture and mortality.
• Current management strategies, including systemic methotrexate and surgery, have limitations such as high failure rates and bleeding risks.
• Standardized treatment protocols for interstitial pregnancy are lacking, necessitating exploration of alternative approaches.

Purpose of the Study:

• To report a successful case of interstitial ectopic pregnancy treated with a combined minimally invasive technique.
• To describe the specific technique and unique medical management for a high-risk patient with a bleeding disorder.
• To highlight the potential benefits of combined local methotrexate injection and uterine artery embolization.

Main Methods:

• A case report of a 28-year-old female with interstitial ectopic pregnancy and a known bleeding disorder.
• Combined treatment involving local injection of methotrexate (MTX) and uterine artery embolization (UAE).
• Detailed description of the procedural technique and management of the bleeding disorder during treatment.

Main Results:

• Successful treatment of interstitial ectopic pregnancy with the combined MTX and UAE approach.
• No significant bleeding complications or recurrence reported in the patient.
• Demonstrated feasibility and efficacy of the minimally invasive technique in a high-risk patient.

Conclusions:

• Combined local MTX injection and UAE represent a safe and effective minimally invasive treatment for interstitial ectopic pregnancy.
• This approach may offer improved success rates and reduced risks compared to traditional methods, particularly in complex cases.
• Further research is warranted to establish this combined technique as a standard treatment option, especially for patients with contraindications to surgery or bleeding disorders.