[Quantitative evaluation of a SEIR model for forecasting COVID-19 cases]
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A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
Gustavo Pereyra Irujo1, Luciano Velázquez2, Andrea Perinetti3
1CONICET. Instituto Nacional de Tecnología Agropecuaria, Balcarce, Argentina.
Introduction:
Epidemiological models have been widely used during the COVID-19 pandemic, although performance evaluation has been limited. The objective of this work was to thoroughly evaluate a SEIR model used for the short-term (1 to 3 weeks) prediction of cases, quantifying its actual past performance, and its potential performance by optimizing the model parameters.
Methods:
Daily case forecasts were obtained for the first wave of cases (July 31, 2020 to March 11, 2021) in the district of General Pueyrredón (Argentina), quantifying the model performance in terms of uncertainty, inaccuracy and imprecision. The evaluation was carried out with the original parameters of the model (used in the forecasts that were published), and also varying different parameters in order to identify optimal values.
Results:
The analysis of the model performance showed that alternative values of some parameters, and the correction of the input values using a "moving average" filter to eliminate the weekly variations in the case reports, would have yielded better results. The model with the optimized parameters was able to reduce the uncertainty from almost 40% to less than 15%, with similar values of inaccuracy, and with slightly greater imprecision.
Discussion:
Simple epidemiological models, without large requirements for their implementation, can be very useful for making quick decisions in small cities or cities with limited resources, as long as the importance of their evaluation is taken into account and their scope and limitations are considered.
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