Arfid Genes and Environment (ARFID-GEN): Study Protocol
Cynthia M Bulik1, Nadia Micali2, Casey M MacDermod1
1University of North Carolina at Chapel Hill.
Research Square
|September 11, 2023
Summary
The ARFID-GEN study investigates genetic and environmental factors in Avoidant Restrictive Food Intake Disorder (ARFID). This large-scale genetic analysis aims to uncover actionable insights into ARFID
Area of Science:
- Genetics
- Psychiatry
- Pediatrics
Background:
- The Avoidant Restrictive Food Intake Disorder Genes and Environment (ARFID-GEN) study examines genetic and environmental risk factors for ARFID.
- ARFID affects children and adults, necessitating research into its complex etiology.
Approach:
- Recruiting 3,000 US-based children and adults with ARFID for online phenotyping and consent.
- Collecting saliva samples for genotyping and conducting a genome-wide association study.
- Analyzing genetic architecture of ARFID in relation to other disorders.
Key Points:
- Investigating genetic and environmental contributions to ARFID.
- Comparing ARFID's genetic basis with other eating disorders, neurodevelopmental, and metabolic traits.
- Utilizing genome-wide association studies for comprehensive genetic analysis.
Conclusions:
- ARFID-GEN aims to provide clinically meaningful insights into ARFID.
- The study seeks to advance the understanding of eating disorder genetics.
- Findings will elucidate the genetic architecture of ARFID.
Keywords:
avoidant restrictive food intake disordereating disordersgenome-wide associationpicky eatingpsychiatric geneticspsychiatric genomics consortiumselective eatingsocial mediaMore Related Videos
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