Cystic lesions associated with meningiomas

Area of Science:

• Neurosurgery
• Neuropathology
• Neuroradiology

Background:

• Meningiomas are the most common primary tumors of the central nervous system.
• Large cysts associated with meningiomas are rare but present diagnostic and surgical challenges.

Observation:

• This study reviews three cases of meningiomas with large cysts and 58 additional cases from the literature.
• Analysis focuses on surgical and pathological findings to understand cyst etiology.
• Preoperative diagnosis using computed tomography (CT) hypodensities is discussed, differentiating from other cystic tumors.

Findings:

• The absence of a capsule between the meningioma and the cyst during surgery is a key indicator of an intratumoral cyst.
• Histological evaluation of cyst walls may be required for definitive diagnosis in ambiguous cases.

Implications:

• Understanding the intratumoral nature of these cysts is crucial for appropriate surgical management.
• Accurate preoperative diagnosis can guide surgical planning and improve patient outcomes.
• Further research into the pathogenesis of cystic meningiomas may reveal new therapeutic targets.