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Related Concept Videos

Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

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The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...
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Direct Motor Pathways01:11

Direct Motor Pathways

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The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
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Indirect Motor Pathways01:22

Indirect Motor Pathways

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The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
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Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

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Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
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Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

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Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
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Auditory Pathway01:15

Auditory Pathway

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Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
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Updated: Jul 15, 2025

Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats
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Three Laboratory Procedures for Assessing Different Manifestations of Impulsivity in Rats

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A thalamocortical pathway controlling impulsive behavior.

Robertas Guzulaitis1, Lucy M Palmer2

  • 1Life Sciences Center, Vilnius University, Vilnius, LT-10257, Lithuania.

Trends in Neurosciences
|October 1, 2023
PubMed
Summary
This summary is machine-generated.

Anticipating movements is key, but uncontrolled anticipation can cause impulsive actions. New research highlights the ventromedial thalamus and anterior lateral motor cortex in controlling this behavior in mice.

Keywords:
anterior lateral motor cortex (ALM)brain statescerebral cortexdendritic integrationimpulsive actionventromedial (VM) thalamus

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Area of Science:

  • Neuroscience
  • Behavioral Neuroscience
  • Motor Control

Background:

  • Motor actions require planning and anticipation for accuracy.
  • Uncontrolled anticipation can lead to impulsive behaviors, defined as poorly conceived, risky actions.
  • Traditionally, the frontal cortex and basal ganglia were considered primary control centers for impulsive behavior.

Purpose of the Study:

  • To explore the newly discovered role of the ventromedial (VM) thalamus and anterior lateral motor cortex (ALM) in impulsive behavior.
  • To investigate the involvement of the thalamocortical pathway in controlling impulsive actions.
  • To suggest potential cellular mechanisms underlying cortical activity related to impulsive behavior.

Main Methods:

  • The study focuses on exploring the role of specific brain regions in mice.
  • It investigates the thalamocortical pathway's contribution to impulsive behavior.
  • Cellular mechanisms driving cortical activity are considered.

Main Results:

  • The ventromedial (VM) thalamus and anterior lateral motor cortex (ALM) play a significant role in controlling impulsive behavior in mice.
  • The thalamocortical pathway is implicated in the regulation of impulsive actions.
  • Specific cellular mechanisms are proposed to underlie the observed cortical activity.

Conclusions:

  • The ventromedial thalamus and anterior lateral motor cortex are crucial for regulating impulsive behavior.
  • The thalamocortical pathway represents a key neural circuit for controlling anticipation and preventing impulsive actions.
  • Understanding these pathways offers insights into the cellular basis of impulsive behavior.