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Updated: Jul 13, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
Confocal Microscopy, Anterior Segment Optical Coherence Tomography and Clinical Findings in a Non-Granulomatous
Marcel Y Avila1, Laura J Gallego-Suarez1
1Department of Ophthalmology, School of Medicine Universidad Nacional de Colombia, Bogotá, Colombia.
Purpose:
To report a rare case of non-granulomatous anterior uveitis (clinical, IVCM in vivo confocal microscopy, and anterior optical coherence tomography (OCT) findings) in a non-immunosuppressed patient with mpox infection.
Methods:
A 24-year-old male was consulted for bilateral ocular pain, red eye, itchiness, and mucoid discharge. In his left eye, multiple vesicles and papules, some with central ulceration, were found in the superior and inferior eyelids. Mucoid discharge, chemosis, limbitis, and an anterior chamber reaction were also found. A conjunctival PCR swab for mpox was positive. The patient was treated with topical steroids with a good response.
Results:
OCT and IVCM showed sub-endothelial deposits, stromal edema, hyperreflective multinucleated images in the epithelial layer, activated stromal images, and stromal edema characterized by fusiform hyperreflectivity that was resolved with the proposed treatment.
Conclusions:
This is the first report of OCT and IVCM in a non-immunosuppressed patient with mpox infection with a good response to topical steroids.

