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Published on: July 29, 2021
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Evaluating Stage Motion for Automated Electron Microscopy
Kevin R Fiedler1,2, Matthew J Olszta2, Kayla H Yano2
1College of Arts and Sciences, Washington State University-Tri-Cities, Richland, WA 99354, USA.
Summary
Automating transmission electron microscope (TEM) stage movements for self-driving operation is challenging due to mechanical instability. This study presents a framework to evaluate TEM stage motion and identify limitations for achieving full autonomy.
Area of Science:
- Materials Science
- Microscopy
- Automation and Control
Background:
- Self-driving transmission electron microscopes (TEMs) require precise and rapid stage movements for autonomous operation.
- Current TEM stage automation is hindered by mechanical instability, hysteresis, and thermal drift, limiting AI-directed designs.
Purpose of the Study:
- To develop a general framework for evaluating stage motion in any TEM.
- To identify rate-limiting factors for achieving full autonomy in TEM stage control.
- To guide the design of future self-driving TEM instruments.
Main Methods:
- Defining metrics to quantify TEM stage degrees of freedom.
- Analyzing existing TEM stage mechanisms to understand performance limitations.
- Proposing solutions to enhance stage movement precision and repeatability.
Main Results:
- A framework for evaluating TEM stage motion performance has been established.
- Key challenges in achieving precise, automated stage movements were identified.
- Potential solutions for improving stage control were proposed.
Conclusions:
- Understanding and addressing mechanical limitations are crucial for autonomous TEM operation.
- The developed framework can guide the design of more capable self-driving TEMs.
- Fundamental limits of current hardware for automated experimentation were discussed.

