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Test-retest repeatability in macular retinal oximetry.
Jennyffer D Smith1, Kelly Bisignano1, Wendy W Harrison1
1Department of Optometry, University of Houston College of Optometry, Houston, TX, USA.
Clinical & Experimental Optometry
|October 16, 2023
Summary
The Zilia oximeter shows good test-retest repeatability for macular oxygen saturation in healthy adults. Multiple readings may be necessary for precise retinal oximetry measurements.
Area of Science:
- Ophthalmology
- Medical Devices
- Physiology
Background:
- Evaluating retinal macular oxygen saturation in healthy individuals is crucial for understanding vascular diseases like diabetes.
- Localised retinal oximetry provides insights into macular health.
Purpose of the Study:
- To assess the test-retest repeatability of the Zilia Oximeter for retinal oximetry in healthy adults.
- To evaluate macular oxygen saturation measurements in different racial groups aged 18-40 years.
Main Methods:
- Twenty-seven healthy adults (mean age 26.3 years) underwent retinal oximetry using the Zilia device.
- Measurements were taken at four macular locations, repeated twice on the same day and again 1-2 weeks later.
- Intraclass correlation, Bland-Altman repeatability coefficient, and coefficient of variation were used for analysis.
Main Results:
- The average intraclass correlation across three measurement times was 0.78.
- The averaged intrasubject repeatability coefficient was 8.4, with a coefficient of variation of 5.4%.
Conclusions:
- The Zilia oximeter demonstrates good test-retest repeatability for macular oxygen saturation measurements.
- While repeatable, clinicians may need to obtain multiple readings to ensure accuracy in retinal oximetry.
