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Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
New Biomarkers for Cardiovascular Disease
Stephanie J Kim1,2, Fernanda C P Mesquita1, Camila Hochman-Mendez1
1Department of Regenerative Medicine Research, The Texas Heart Institute, Houston, Texas.
Insights
Cardiovascular disease (CVD) remains a global health crisis. Novel exosome biomarkers show promise for earlier and more accurate CVD detection, improving patient outcomes.
Area of Science:
- Biomedical research
- Cardiovascular medicine
- Biomarker discovery
Background:
- Cardiovascular disease (CVD) is the primary cause of global mortality and morbidity.
- Increasing CVD prevalence, driven by an aging population, necessitates improved diagnostic tools.
- Current CVD biomarkers like cardiac troponin and cytokines have limitations in sensitivity and specificity.
Conclusions:
- Exosomes represent a significant advancement in cardiovascular disease biomarker research.
- Further development and clinical integration of exosome biomarkers are warranted.
- Targeting exosomes could revolutionize cardiovascular disease diagnosis and management.
Abstract:
Cardiovascular disease is the leading cause of death and disability worldwide. Early detection and treatment of cardiovascular disease are crucial for patient survival and long-term health. Despite advances in cardiovascular disease biomarkers, the prevalence of cardiovascular disease continues to increase worldwide as the global population ages. To address this problem, novel biomarkers that are more sensitive and specific to cardiovascular diseases must be developed and incorporated into clinical practice. Exosomes are promising biomarkers for cardiovascular disease. These small vesicles are produced and released into body fluids by all cells and carry specific information that can be correlated with disease progression. This article reviews the advantages and limitations of existing biomarkers for cardiovascular disease, such as cardiac troponin and cytokines, and discusses recent evidence suggesting the promise of exosomes as cardiovascular disease biomarkers.
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