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Probiotics Show Promise as a Novel Natural Treatment for Neurological Disorders
Preeti Jha1, Neha Dangi2, Shikha Sharma3
1Department of Biotechnology, Amity Institute of Biotechnology, Amity University, Jaipur, 303002, Rajasthan, India.
Current Pharmaceutical Biotechnology
|October 25, 2023
Summary
Probiotics, known as psychobiotics, positively impact mental health by influencing the gut-brain axis. This review explores their potential in managing neurological disorders.
Area of Science:
- Microbiology
- Neuroscience
- Psychiatry
Background:
- Probiotics are beneficial microorganisms that confer health advantages when consumed regularly.
- These microorganisms produce metabolites with nutritional and medicinal properties.
- Emerging research links probiotics to improvements in mental health outcomes like anxiety and depression.
Purpose of the Study:
- To review the current scientific evidence on the use of probiotics for neurological disorders.
- To explore the role of psychobiotics in modulating the gut-brain axis.
- To assess the therapeutic potential of probiotics in psychiatric and neurological conditions.
Main Methods:
- Systematic review of existing scientific literature.
- Analysis of studies investigating the gut-brain axis communication pathways.
- Examination of probiotic strains' effects on the central nervous system (CNS).
Main Results:
- Probiotics, or psychobiotics, can influence mental health through the gut-brain axis (GBA).
- Specific bacterial and yeast strains modulate CNS communication via neuronal, humoral, and metabolic pathways.
- Evidence suggests probiotics may help alleviate mood and anxiety symptoms.
Conclusions:
- Psychobiotics represent a promising therapeutic avenue for neurological and psychiatric disorders.
- Further research is needed to validate the efficacy of probiotics in treating these conditions.
- The gut-brain axis offers a novel target for developing new treatments for mental health issues.
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