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Mobile health interventions in multiple sclerosis: A systematic review.
Christoph Heesen1, Thomas Berger2, Karin Riemann-Lorenz1
1Clinical and Rehabilitative MS Research, Institute of Neuroimmunology and Multiple Sclerosis, University Medical Center, Hamburg, Germany.
Summary
Digital health tools show promise for multiple sclerosis (MS) management, with specific interventions for depression and fatigue demonstrating significant patient-reported outcomes. Further research is needed to confirm efficacy and guide implementation into routine care.
Area of Science:
- Digital Health
- Neuroscience
- Rehabilitation Medicine
Background:
- Persons with multiple sclerosis (pwMS) are often younger and less disabled than patients with other chronic diseases, making them suitable candidates for digital health applications.
- Numerous digital health applications have been developed for pwMS to manage their condition.
Conclusions:
- Mobile, self-guided digital health applications have been tested in RCTs for pwMS.
- Two interventions for depression and fatigue show significant effects, but implementation into routine care remains a challenge.

