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Updated: Jul 12, 2025
Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
Published on: December 15, 2017
Small bowel imaging in inflammatory bowel disease: updates for 2023
Maira Hameed1,2, Stuart A Taylor1,2
1Centre for Medical Imaging, University College London, United Kingdom.
Cross-sectional imaging is crucial for managing Crohn's disease, assessing activity, and guiding treatment. Future research should focus on integrating advanced imaging techniques, including artificial intelligence, for precise patient care and therapeutic targets like transmural healing.
Area of Science:
- Gastroenterology
- Radiology
- Medical Imaging
Background:
- Cross-sectional imaging (MR/CT enterography, ultrasound) is vital for Crohn's disease management.
- These techniques evaluate bowel wall, surrounding tissues, and complications.
- The role of imaging is expanding with a focus on transmural healing as a therapeutic goal.
Purpose of the Study:
- To review evidence on cross-sectional imaging in Crohn's disease.
- To cover emerging applications like motility/fibrosis quantification and AI.
- To discuss integration of advances and identify research gaps.
Main Methods:
- Literature search of MEDLINE and Web of Science (2012-2023).
- Review of evidence for disease activity, phenotyping, and treatment response.
- Discussion of novel imaging applications and consensus statements.
Main Results:
- Established role of cross-sectional imaging in Crohn's disease.
- Emerging applications include motility, fibrosis, prognostication, and AI.
- Need for standardized reporting and definitions of transmural healing.
Conclusions:
- Cross-sectional imaging is integral to Crohn's disease care.
- Future research should prioritize clinical integration, standardized definitions, and novel techniques like AI.
- Focus on imaging-based targets such as transmural healing and stricturing disease phenotyping is essential.
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