Related Experiment Video

Updated: Jul 10, 2025

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:15

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

72

Risk Factors and Predictive Model for Mortality of Hospitalized COVID-19 Elderly Patients from a Tertiary Care

Mallika Chuansangeam1, Bunyarat Srithan1, Pattharawin Pattharanitima1

  • 1Department of Internal Medicine, Faculty of Medicine, Thammasat University Hospital, Thammasat University, Pathum Thani 12120, Thailand.

Medicines (Basel, Switzerland)
|November 24, 2023
PubMed

Insights

A new risk score accurately identifies elderly COVID-19 patients at high risk of death. This tool aids early clinical decisions for hospitalized seniors with COVID-19, improving mortality prediction.

Area of Science:

  • Gerontology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Elderly patients with COVID-19 face a high mortality risk.
  • Early identification of high-risk individuals is crucial for timely clinical intervention.
  • This study focuses on predicting in-hospital mortality in this demographic.

Purpose of the Study:

  • To identify risk factors for all-cause in-hospital mortality in elderly COVID-19 patients.
  • To develop a predictive scoring system for mortality risk assessment.
  • To validate the accuracy of the developed risk score.

Main Methods:

  • Retrospective review of 138 hospitalized elderly COVID-19 patients (age > 60).
  • Multivariate logistic regression to identify independent predictors of mortality.
  • Development of a weighted integer risk score based on identified variables.

Main Results:

  • Four key variables (age, respiratory rate, glomerular filtration rate, stroke history) were identified as predictors.
  • The developed scoring system demonstrated high accuracy with an AUROC of 0.9415.
  • A risk score exceeding 213 was established as a threshold for high mortality risk.

Conclusions:

  • A simple predictive risk score can accurately assess mortality risk upon admission.
  • This tool offers a valuable initial assessment for hospitalized elderly COVID-19 patients.
  • The scoring system supports informed clinical decision-making for high-risk individuals.

Keywords:
COVID-19elderlymortalitypredictive model

More Related Videos

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

7.1K
Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

569

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
246
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.9K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
240
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
4.2K
Assumptions of Survival Analysis01:15

Assumptions of Survival Analysis

Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
135
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.1K