The skin changes in the Crow-Fukase (POEMS) syndrome. A case report

A man with a six-year history of intermittent burning sensations in his legs, hypothyroidism, and peripheral neuropathy also had hypertrichosis, hyperpigmentation, Terry nails, and taut thickened skin of the extremities. Discovery of a plasma cell tumor led to recognition of the Crow-Fukase syndrome, and appropriate treatment with melphalan and prednisone.