Highly flexible and compact volumetric endoscope by integrating multiple micro-imaging devices

Area of Science:

• Medical Devices
• Gastroenterology
• Surgical Technology

Background:

• Light-field endoscopy offers 3D visualization and depth perception for improved surgical and diagnostic accuracy.
• Current light-field endoscopes are limited by rigid, oversized probes, hindering clinical application.
• Minimally invasive procedures require flexible and compact imaging devices for better access and reduced patient discomfort.

Purpose of the Study:

• To develop a highly flexible and compact volumetric endoscope.
• To overcome the limitations of current rigid endoscopic probes.
• To enhance the accuracy and accessibility of in situ lesion diagnosis and surgical interventions.

Main Methods:

• Designed and fabricated a flexible volumetric endoscope using precision-machined multiple micro-imaging devices (MIRDs).
• Packaged the MIRD (5 mm diameter and height) in pliable polyamide with soft data cables for flexibility and protection.
• Evaluated the endoscope's imaging performance, including lateral and axial resolvability, and imaging volume.

Main Results:

• Achieved optimal lateral resolvability of 31 µm and axial resolvability of 255 µm.
• Demonstrated an imaging volume of 2.3 × 2.3 × 10 mm³.
• Successfully verified the device's ability to access internal organs through natural openings in observational experiments on a rabbit's stomach and rectum.

Conclusions:

• The developed flexible and compact volumetric endoscope offers a promising solution for minimally invasive procedures.
• This technology can improve the detection and removal of gastrointestinal tumors and polyps.
• It holds potential for identifying early-stage digestive tract cancers, enhancing patient outcomes.