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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

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Obstructive sleep apnoea-hypopnoea syndrome.

Nicola Read¹, Callum Jennings¹, Alanna Hare¹

¹Royal Brompton Hospital, Kings Health Partnership, London, U.K.

Emerging Topics in Life Sciences

|December 22, 2023

Summary

Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) is a common condition causing airway collapse during sleep, leading to breathing pauses and fragmented sleep. Treatments focus on weight loss and maintaining airway patency.

Keywords:

metabolic syndromes obesity sleep disorders

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Multi-Modal Home Sleep Monitoring in Older Adults

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

Area of Science:

Sleep Medicine
Respiratory Physiology

Background:

Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) is a prevalent disorder.
It involves repetitive collapse of the pharyngeal airway during sleep, causing apnoea or hypopnoea.
This leads to oxygen desaturation and sleep fragmentation.

Purpose of the Study:

To summarize the pathophysiology, clinical presentation, and management of OSAHS.
To highlight the factors influencing upper airway collapsibility in OSAHS patients.

Main Methods:

Review of existing literature on OSAHS.
Analysis of the relationship between airway pressures and collapsibility.
Summary of common diagnostic indicators and treatment modalities.

Main Results:

OSAHS disposition is linked to upper airway collapsibility, influenced by tissue pressures.
Symptoms include snoring, unrefreshing sleep, witnessed apnoeas, choking sensations, and daytime sleepiness.
Consequences span cardiovascular, metabolic, and neurocognitive domains.

Conclusions:

OSAHS is a multifactorial condition with significant health implications.
Effective management requires addressing airway patency through various therapeutic strategies.
Lifestyle changes, particularly weight loss, are crucial components of OSAHS treatment.