Patient-specific mechanical analysis of PCL periodontal membrane: Modeling and simulation

This research fills a knowledge gap in bone tissue engineering by examining the mechanical characteristics of scaffolds at bone-tissue interfaces utilizing a cutting-edge technique involving the creation of 3D scaffolds from Polycaprolactone (PCL). The work employs Finite element analysis to measure the scaffolds' maximum principal and Von Mises stresses and strains. CT scans of the Maxilla and Mandible were used to apply load conditions to 3D models of the upper central incisor. In the derived computational model, four different load situations considered were: the masticatory load (70-100 N at 45°), two parafunctional habits (100-130 N) and 500-550 N at the incisal edge, both at 45°), and a trauma case (800-850 N applied perpendicularly from the inwards direction at 90°). The findings revealed that the central tooth region experiences the highest stress concentration, while the Maxilla and Mandible regions show the least stress. These results provide critical insights into the mechanical behavior of scaffolds at bone-tissue interfaces, suggesting a research direction for developing scaffolds that closely mimic real bone characteristics. The results of this study are particularly significant for using bone replacement materials, providing an approach to more effective healing options for bone traumas and degenerative bone disorders.