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Patient-Reported Outcomes After Vestibular Implantation for Bilateral Vestibular Hypofunction
Andrianna I Ayiotis1, Desi P Schoo2,3, Celia Fernandez Brillet1
1Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, Maryland.
JAMA Otolaryngology-- Head & Neck Surgery
|February 1, 2024
Summary
Vestibular implantation significantly improves dizziness and quality of life for patients with bilateral vestibular hypofunction (BVH). This emerging treatment offers benefits beyond standard care, enhancing daily living for those affected by BVH.
Area of Science:
- Otorhinolaryngology
- Biomedical Engineering
- Neuroscience
Background:
- Standard treatments for bilateral vestibular hypofunction (BVH) are often inadequate.
- Vestibular implantation presents a novel therapeutic approach for BVH patients.
Purpose of the Study:
- To evaluate patient-reported outcomes following prosthetic vestibular stimulation.
- To assess the efficacy of the Multichannel Vestibular Implant (MVI) system.
Main Methods:
- A prospective, single-group cohort study (MVI Early Feasibility Study) involving adults with severe BVH.
- Participants received unilateral MVI implantation, stimulating vestibular nerve branches.
- Outcomes measured included dizziness (DHI), vestibular disability (VADL), and quality of life (SF36U, HUI3).
Main Results:
- MVI recipients showed significant improvements in dizziness, vestibular disability, and HRQOL (SF36U) after 0.5 years.
- Improvements exceeded minimally important differences for DHI, VADL, and SF36U.
- A control group reported no significant changes in these measures, indicating MVI's specific benefit.
Conclusions:
- Vestibular implantation demonstrates patient-reported improvements in vestibular symptoms and quality of life.
- These findings support vestibular implantation as a viable treatment option for bilateral vestibular hypofunction.
- The study highlights the potential of MVI to enhance daily functioning and well-being in BVH patients.
