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The development and technologies of RNA therapeutics
Huong Lan Vuong1, Chu Thanh Lan2, Hien Thi Thu Le3
1Pharmacy Department, National Hospital for Tropical Diseases, Hanoi, Vietnam.
Progress in Molecular Biology and Translational Science
|February 15, 2024
Summary
RNA therapeutics, including small interfering RNAs (siRNAs), offer promising gene silencing for treating diseases. This review covers six categories of RNA-based therapies and delivery strategies for new drug development.
Area of Science:
- Molecular Biology
- Biotechnology
- Genetics
Background:
- Small interfering RNAs (siRNAs) have shown potential in gene silencing for over two decades.
- Advancements in RNA molecular mechanisms, target attachment, and purification have propelled RNA therapeutics.
- RNA therapeutics are increasingly vital for personalized medicine and rare disease treatments.
Conclusions:
- RNA therapeutics represent a rapidly advancing field with significant potential for treating rare and difficult diseases.
- Understanding RNA development and technologies is crucial for future drug discovery.
- This review serves as a reference for researchers in the field of RNA therapeutics.
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