Isolation and characterization of the apolipoprotein genes

These types of studies lay the foundation for understanding the human apolipoproteins at the genetic level. In addition, through a few specific examples, we have already shown evidence at the DNA level that lesions in apolipoprotein genes can play a role in human atherosclerosis. This work is in its infancy but, in the future, we hope it will have a major impact on our ability to understand genetic susceptibility to atherosclerosis in the general population.