Quasi-MOF-Engineered MnO_x/CeBTC Multinanozyme as a Robust Self-Cascade ROS Generator toward Antibacterial Face Mask

Area of Science:

• Materials Science
• Nanotechnology
• Biomedical Engineering

Background:

• Personal protective equipment requires bactericidal properties to combat pathogens.
• Nanozymes offer a promising approach for developing novel nanobactericides through reactive oxygen species (ROS) generation.
• Limited nanozyme designs are specifically tailored for personal protective equipment applications.

Purpose of the Study:

• To construct a multinanozyme for enhanced bactericidal activity in personal protective equipment.
• To investigate the efficacy of a novel manganese oxide nanozyme against bacterial pathogens.
• To explore the potential of nanozymes in combating pathogen invasion at low temperatures.

Main Methods:

• A multinanozyme, MnOₓ/q-CeBTC, was synthesized using a quasi-metal-organic framework (MOF) strategy.
• The nanozyme's structure and properties, including metal cluster exposure and Mn─O─Ce bond formation, were analyzed.
• Enzymatic activities and ROS generation capabilities of the nanozyme were evaluated, particularly at low temperatures.

Main Results:

• The synthesized MnOₓ/q-CeBTC exhibited excellent multiple enzymatic activities and abundant self-cascade ROS generation without H₂O₂.
• The nanozyme demonstrated high efficiency in killing bacteria.
• Incorporation into face masks showed effectiveness in combating pathogen invasion, even at low temperatures.

Conclusions:

• The developed MnOₓ/q-CeBTC nanozyme shows significant potential as an effective bactericide for personal protective equipment.
• The study provides a design strategy for advanced nanozymes with self-cascade ROS generation.
• This research broadens the application of nanozymes in personal protective equipment and other fields.