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Updated: May 6, 2026

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
HEMORRHAGIC UNILATERAL RETINOPATHY: A REPORT OF MULTIMODAL IMAGING IN THREE CASES
Nuria Torrell-Belzach1, Alexandra Miere1, Eric H Souied1
1Department of Ophthalmology, Intercity Hospital, Creteil, France ; and.
Purpose:
The objective of this study was to report three cases of hemorrhagic unilateral retinopathy, diagnosed by multimodal imaging.
Methods:
This was a case report of three patients, two women and one man, aged 51, 74, and 52 years, respectively.
Results:
Symptoms were acute floaters, blurred vision, or central scotoma, unilateral in all cases. The best-corrected visual acuity was 20/20 in the affected eye in two patients with a paracentral scotoma and 20/160 in the third patient. Funduscopic examination revealed multiple unilateral posterior hemorrhages located in the Henle fiber layer in the macula and beneath the internal limiting membrane around the optic disc on spectral domain optical coherence tomography. Fluorescein angiography and indocyanine green angiography did not show any vascular abnormalities. Spectral domain optical coherence tomography angiography did not show any capillary dropout or choroidal abnormalities. In all patients, the visual symptoms completely disappeared within a few weeks, with spontaneous regression of the hemorrhages.
Conclusion:
Hemorrhagic unilateral retinopathy is a rarely reported and poorly understood disorder. Indocyanine green angiography and spectral domain optical coherence tomography angiography did not allow better understanding the condition. No etiology has been associated with this entity so far. The spontaneous resolution of the present cases confirmed the favorable visual prognosis of the condition.
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