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OPTN/SRTR 2022 Annual Data Report: Pancreas.
Raja Kandaswamy1, Peter G Stock2, Jonathan M Miller3
1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Surgery, University of Minnesota, Minneapolis, MN.
Summary
Pancreas transplants declined in 2022, with fewer donors and increased nonuse. Despite this, patient outcomes for pancreas transplants improved, showing better graft survival rates.
Area of Science:
- Transplantation Medicine
- Organ Donation
- Endocrinology
Background:
- Postpandemic recovery in organ transplantation did not extend to pancreas transplants.
- Pancreas transplant numbers in the US decreased in 2022 compared to 2021.
- Declines were observed across simultaneous pancreas-kidney, pancreas-alone, and pancreas-after-kidney procedures.
Purpose of the Study:
- To analyze trends in pancreas transplantation in the United States for 2022.
- To evaluate changes in recipient demographics, donor characteristics, and transplant center volume.
- To assess outcomes of pancreas transplantation, focusing on graft survival rates.
Main Methods:
- Analysis of national pancreas transplant data from 2021 and 2022.
- Examination of donor numbers and nonuse rates.
- Evaluation of graft failure rates and transplant center volume data.
Main Results:
- Total pancreas transplants decreased to 918 in 2022 from 963 in 2021.
- Simultaneous pancreas-kidney transplants decreased to 810, and pancreas-alone transplants dropped to 62.
- Despite decreased utilization, 1-year graft survival for simultaneous pancreas-kidney transplants improved to 8.1% (pancreas) and 4.3% (kidney).
Conclusions:
- Pancreas transplantation faced a decline in 2022, contrary to other organ transplants.
- A decrease in pancreas donors and an increase in nonuse rates contributed to the overall decline.
- Transplant outcomes continue to improve, indicating advancements in surgical and post-transplant care.
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