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Development of a Small-Footprint 50 MHz Linear Array: Fabrication and Micro-Ultrasound Imaging Demonstration.

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Sensors (Basel, Switzerland)
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Summary

A novel interconnection method enables compact, high-frequency ultrasound arrays for medical imaging. This technique significantly reduces the footprint of ultrasound probes, allowing for smaller, more effective endoscopic devices.

Keywords:
acoustic characterizationelectrical characterizationelectrode patterningexcimer laserfine pitchflexible-circuit cablinghigh-density interconnecthigh-frequency ultrasoundlaser machiningmetal depositionminiaturizationpolyimidetransducer array

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Area of Science:

  • Biomedical Engineering
  • Ultrasound Technology
  • Medical Device Fabrication

Background:

  • Compact high-frequency arrays are crucial for clinical and preclinical applications requiring small-footprint or endoscopic devices.
  • Current fabrication methods for compact arrays lead to increased footprint due to interconnections.
  • Existing methods like wire bonding and conductive adhesives are not optimal for miniaturization.

Purpose of the Study:

  • To develop a novel interconnection method for fabricating compact, high-frequency ultrasound arrays.
  • To achieve a right-angle, compact, and reliable connection between array elements and flexible circuits.
  • To reduce the overall footprint of the ultrasound array for improved endoscopic applications.

Main Methods:

  • Utilized vacuum-deposited metals, laser patterning, and electroplating for interconnection.
  • Thickened array element edges with patterned copper traces to enhance connection.
  • Fabricated a 2.3 mm x 1.7 mm, 64-element linear array with a 36 μm pitch.

Main Results:

  • The interconnect added only 100 μm to each side of the array.
  • Achieved an average center frequency of 55 MHz with a -6 dB bandwidth of 41%.
  • Measured imaging resolutions of 35 μm (axial) and 114 μm (lateral).

Conclusions:

  • The proposed interconnection method enables the fabrication of significantly more compact high-frequency ultrasound arrays.
  • Demonstrated successful ex vivo and in vivo imaging, validating the performance of the developed arrays.
  • This advancement facilitates the development of smaller, more effective endoscopic ultrasound devices for various medical applications.