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Antidiabetic Property Optimization from Green Leafy Vegetables Using Ultrasound-Assisted Extraction to Improve
Wahyu Haryati Maser1,2, Nur Maiyah1, Supatra Karnjanapratum3
1School of Food Industry, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.
Preventive Nutrition and Food Science
|April 5, 2024
Summary
This study optimized ultrasound-assisted extraction of antidiabetic compounds from vegetables for use in crackers. The best crackers, containing 2.5% extract and baked at 140°C, showed significant antidiabetic and antioxidant effects.
Area of Science:
- Food Science
- Nutritional Biochemistry
- Extraction Technology
Background:
- Diabetes management is a global health challenge.
- Natural antidiabetic compounds exist in vegetables.
- Developing functional foods for diabetes control is crucial.
Purpose of the Study:
- To optimize ultrasound-assisted extraction of antidiabetic compounds from spring onions, bunching onions, and celery.
- To incorporate these extracts into crackers to create a functional antidiabetic snack food.
- To evaluate the bioactivity of the resulting crackers.
Main Methods:
- Ultrasound-assisted extraction (UAE) was optimized for ethanol concentration, amplitude, and sonication time.
- Extracts were incorporated into crackers at varying percentages (0.625%, 1.25%, 2.5%).
- Crackers were baked at different temperatures (140°C, 150°C, 160°C), and their physical characteristics and bioactivities were analyzed.
Main Results:
- Optimal UAE conditions yielded high α-glucosidase inhibitory activity (1,449.73 mmol ACE/g) and extraction yield (24.16%).
- Crackers with 2.5% vegetable extract baked at 140°C exhibited the highest total phenolic content and antioxidant activity.
- These optimized crackers demonstrated significant antidiabetic and antiobesity effects.
Conclusions:
- Effective conditions for ultrasound-assisted extraction of antidiabetic compounds from vegetables were established.
- A method for preparing functional antidiabetic crackers using these vegetable extracts was developed.
- This research offers a promising approach to creating novel functional snack foods for diabetes management.

