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Quantification of the Bioactivity of Ethanolic Extract From Phoenix dactylifera
Jeesha Soni1, Suganya Panneer Selvam1, Rajeshkumar Shanmugam2
1Department of Oral Biology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.
Aim:
This study aims to quantitatively assess the anti-inflammatory and antioxidant activities of the ethanolic extract of Phoenix dactylifera seeds.
Materials And Methods:
Around 30 seeds of Phoenix dactylifera were collected, crushed, and powdered; 10 gm of powder was added to 100 ml of ethanolic extract and boiled for further analysis. Egg albumin denaturation assay and hydroxyl radical scavenging assay were done to evaluate the anti-inflammatory and antioxidant activity, respectively. An independent t-test was used to compare the anti-inflammatory and antioxidant potential of the ethanolic extract of Phoenix dactylifera using SPSS Statistics version 22.0 (IBM Corp. Released 2013. IBM SPSS Statistics for Windows, Version 22.0; Armonk, NY: IBM Corp.), and values less than 0.05 are considered statistically significant.
Results:
The seeds of Phoenix dactylifera have potent anti-inflammatory and antioxidant properties. Both anti-inflammatory and antioxidant properties improved with higher concentrations and were comparable to the control substances diclofenac sodium, vitamin E, and ascorbic acid, respectively. The most significant anti-inflammatory and antioxidant effect was observed at a dosage of 50 μL, with a p-value of 0.001.
Conclusion:
To conclude, we found that the ethanolic extract of Phoenix dactylifera has anti-inflammatory and antioxidant activity, which can further be used for the improvement of pharmaceuticals.
