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Updated: Jun 28, 2025

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
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Self-Reported Disability Type and Risk of Alcohol-Induced Death - A Longitudinal Study Using Nationally

Jonathan Aram1, Natalie Slopen2, Candace Cosgrove3

  • 1Department of Epidemiology and Biostatistics, University of Maryland School of Public Health, USA.

Substance Use & Misuse
|April 18, 2024
PubMed
Summary
This summary is machine-generated.

Adults with disabilities face a higher risk of alcohol-induced death, particularly those with complex activity, vision, or mobility limitations. Prevention strategies should target these high-risk groups for tailored interventions.

Keywords:
Alcohol drinkingdisabled personsepidemiologymortalitymortality disparities in American communities study

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Area of Science:

  • Public Health
  • Epidemiology
  • Disability Studies

Background:

  • Disability is linked to alcohol misuse and drug overdose deaths.
  • The association between disability and alcohol-induced death is understudied.

Purpose of the Study:

  • To quantify the risk of alcohol-induced death among US adults with various types of disabilities.
  • To identify specific disability types associated with elevated alcohol-induced mortality risk.

Main Methods:

  • Analysis of a nationally representative longitudinal sample of US adults (Mortality Disparities in American Communities study, n=3,324,000).
  • Mortality outcomes ascertained through the National Death Index from 2008 to 2019.
  • Adjusted hazard ratios (aHRs) estimated for disability type and alcohol-induced death, controlling for covariates.

Main Results:

  • 4000 alcohol-induced deaths occurred during 12 years of follow-up.
  • Highest risks observed for complex activity limitation (aHR=1.7), vision limitation (aHR=1.6), and mobility limitation (aHR=1.4).
  • Cognitive and hearing limitations showed smaller, non-significant associations with alcohol-induced death.

Conclusions:

  • The risk of alcohol-induced death significantly varies by disability type.
  • Prevention efforts should prioritize adults with complex activity, vision, mobility, or multiple limitations.
  • Tailored interventions, including early alcohol use disorder treatment and improved access to opportunities, are recommended.