Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nucleic Acids02:43

Nucleic Acids

7.5K
7.5K
Nucleic Acid Structure01:25

Nucleic Acid Structure

6.1K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
6.1K
Nucleic acids02:43

Nucleic acids

161.9K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
161.9K
Nucleic Acids and Nucleotides01:20

Nucleic Acids and Nucleotides

9.0K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and have instructions for its functioning. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria....
9.0K
DNA Isolation01:34

DNA Isolation

192.9K
DNA from cells is required for many biotechnology and research applications, such as molecular cloning. To remove and purify DNA from cells, researchers use various methods of DNA extraction. While the specifics of different protocols may vary, some general concepts underlie the process of DNA extraction.
192.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diverse, distinct, and densely packed DNA nanostar droplets.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Condensation and activator/repressor control of a transcription-regulated biomolecular liquid.

Soft matter·2025
Same author

Cooperation and Competition of Base Pairing and Electrostatic Interactions in Mixtures of DNA Nanostars and Polylysine.

Journal of the American Chemical Society·2025
Same author

Nucleation dynamics of a model biomolecular liquid.

The Journal of chemical physics·2024
Same author

Controlling the size and adhesion of DNA droplets using surface- enriched DNA molecules.

Soft matter·2024
Same author

Controlling liquid-liquid phase behaviour with an active fluid.

Nature materials·2023
Same journal

Switchable band alignment in 2D-perovskite/WS<sub>2</sub>heterostructures for tunable exciton transport and valley polarization.

Reports on progress in physics. Physical Society (Great Britain)·2026
Same journal

Chiral graviton modes in fermionic Fractional Chern Insulators.

Reports on progress in physics. Physical Society (Great Britain)·2026
Same journal

Bound states in the continuum in plasmonic structures.

Reports on progress in physics. Physical Society (Great Britain)·2026
Same journal

Unlocking complex optical vortices with flat optics.

Reports on progress in physics. Physical Society (Great Britain)·2026
Same journal

Pseudo-Hermitian magnon dynamics.

Reports on progress in physics. Physical Society (Great Britain)·2026
Same journal

Uniaxial-stress-induced magnetic transitions in the triangular-lattice antiferromagnet PdCrO<sub>2</sub>.

Reports on progress in physics. Physical Society (Great Britain)·2026
See all related articles

Related Experiment Video

Updated: Jun 27, 2025

Locked Nucleic Acid Flow Cytometry-fluorescence in situ Hybridization LNA flow-FISH: a Method for Bacterial Small RNA Detection
09:45

Locked Nucleic Acid Flow Cytometry-fluorescence in situ Hybridization LNA flow-FISH: a Method for Bacterial Small RNA Detection

Published on: January 10, 2012

25.4K

Nucleic acid liquids.

Gabrielle R Abraham1, Aria S Chaderjian1, Anna B N Nguyen2

  • 1Physics Department,University of California, Santa Barbara, CA 93106, United States of America.

Reports on Progress in Physics. Physical Society (Great Britain)
|May 2, 2024
PubMed
Summary
This summary is machine-generated.

Nucleic acid (NA) liquids, formed via base-pairing or coacervation, offer tunable properties for soft materials. Engineered NAs enable customizable liquid behaviors for novel applications in physics and materials science.

Keywords:
DNA self assemblybiomolecular liquidsnucleic acidsphase transitions

More Related Videos

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication
05:33

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

Published on: July 5, 2024

652
NanoDrop Microvolume Quantitation of Nucleic Acids
09:28

NanoDrop Microvolume Quantitation of Nucleic Acids

Published on: November 22, 2010

202.2K

Related Experiment Videos

Last Updated: Jun 27, 2025

Locked Nucleic Acid Flow Cytometry-fluorescence in situ Hybridization LNA flow-FISH: a Method for Bacterial Small RNA Detection
09:45

Locked Nucleic Acid Flow Cytometry-fluorescence in situ Hybridization LNA flow-FISH: a Method for Bacterial Small RNA Detection

Published on: January 10, 2012

25.4K
Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication
05:33

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

Published on: July 5, 2024

652
NanoDrop Microvolume Quantitation of Nucleic Acids
09:28

NanoDrop Microvolume Quantitation of Nucleic Acids

Published on: November 22, 2010

202.2K

Area of Science:

  • Biomolecular condensates
  • Soft matter physics
  • Nucleic acid nanotechnology

Background:

  • Recent discoveries highlight biomolecular liquid roles in biological systems.
  • Advanced nucleic acid (NA) synthesis enables precise modification.
  • Growing interest in liquid phases of NAs due to these advances.

Purpose of the Study:

  • Review the emerging field of nucleic acid liquids.
  • Discuss theoretical underpinnings and material properties.
  • Highlight functional applications and future challenges.

Main Methods:

  • Formation of NA liquids via base-pairing interactions.
  • Formation of NA liquids via coacervation with charged molecules.
  • Utilizing sequence-engineered NAs to tune liquid properties.

Main Results:

  • NA liquids exhibit tunable microscopic particle properties.
  • Engineered NAs imbue customizable behaviors into liquid phases.
  • Applications span fundamental physics problems and novel material creation.

Conclusions:

  • NA liquids represent a versatile platform for soft materials.
  • Further research is needed to address open questions and challenges.
  • This field holds significant potential for structured and multi-functional materials.