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Updated: Jun 27, 2025
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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
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Sex-specific differences in presenting symptoms of obstructive sleep apnea
Abhishek Goyal1, Rishikesh Meena1, Suruchi Gupta2
1Pulmonary Medicine, AIIMS Bhopal, Madhya Pradesh, India.
Summary
Obstructive Sleep Apnea (OSA) affects women differently, with females being older, more obese, and experiencing more severe symptoms like morning headaches and depression. They also show higher apnea-hypopnea index (AHI) than men.
Area of Science:
- Sleep Medicine
- Pulmonology
- Internal Medicine
Background:
- Limited data exists on gender-specific Obstructive Sleep Apnea (OSA) presentation in India.
- Understanding these differences is crucial for accurate diagnosis and tailored treatment.
Purpose of the Study:
- To compare general characteristics and presenting symptoms between male and female OSA patients in India.
- To identify key gender-based disparities in OSA presentation.
Main Methods:
- Retrospective analysis of 514 diagnosed OSA patients (367 males, 147 females).
- Comparison of patient history, biochemical reports, and polysomnography variables between genders.
Main Results:
- Females were older (55.97 vs. 50.2 years) and more obese (BMI 35.26 vs. 29.58 kg/m²).
- Females reported higher prevalence of morning headache, nocturia, fatigability, and depression.
- Females exhibited a significantly higher Apnea-Hypopnea Index (AHI) (P=0.01).
Conclusions:
- Indian women with OSA present with greater obesity, advanced age, and higher fasting blood glucose.
- Females experience more frequent fatigability, depression, nocturia, and morning headaches.
- Women with OSA demonstrate more severe disease, indicated by a higher AHI.
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