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Related Concept Videos

The ABO Blood Group01:12

The ABO Blood Group

1.7K
The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
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Blood Types02:20

Blood Types

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
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Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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Related Experiment Video

Updated: Jun 26, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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An update to Kidd blood group system.

Janis R Hamilton1

  • 1Immunohematology Reference Laboratory, American Red Cross, Detroit, MI, US.

Immunohematology
|May 13, 2024
PubMed
Summary
This summary is machine-generated.

Recent advancements have expanded knowledge of the Kidd blood group system, including gene structure, rare phenotypes, and its clinical importance in transplantation and pregnancy. This review covers these new findings.

Keywords:
JKJK blood groupKiddKidd blood group

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Area of Science:

  • Immunology
  • Genetics
  • Transfusion Medicine

Background:

  • The Kidd blood group system is crucial in transfusion medicine and understanding blood group genetics.
  • Previous reviews have provided foundational knowledge, but significant new discoveries have emerged since 2015.

Purpose of the Study:

  • To provide an updated comprehensive review of the Kidd blood group system.
  • To detail recent advancements in gene structure, allelic variations, and associated phenotypes.
  • To discuss the clinical significance of the Kidd system in specific medical contexts.

Main Methods:

  • Literature review of recent publications on the Kidd blood group system.
  • Analysis of studies focusing on gene structure and variant alleles.
  • Synthesis of clinical data regarding transfusion reactions, renal transplantation, and hemolytic disease of the fetus and newborn.

Main Results:

  • New insights into the genetic basis of Kidd blood group phenotypes, including null and variant expressions.
  • Demonstrated clinical relevance of Kidd antibodies in transfusion reactions and transplantation.
  • Emerging understanding of Kidd blood group antigens' role in urea transport in non-renal tissues.

Conclusions:

  • The Kidd blood group system continues to evolve with new genetic and clinical discoveries.
  • Updated knowledge is essential for accurate immunohematology practice and patient care.
  • Further research into Kidd antigen function may reveal broader physiological roles.