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Updated: Jun 26, 2025
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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
N-Oxide-to-Carbon Transmutations of Azaarene N-Oxides
Nicholas A Falcone1, Sam He1, John F Hoskin1
1Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
Abstract:
Reactions that change the identity of an atom within a ring system are emerging as valuable tools for the site-selective editing of molecular structures. Herein, we describe the expansion of an underdeveloped transformation that directly converts azaarene-derived N-oxides to all-carbon arenes. This ring transmutation exhibits good functional group tolerance and replaces the N-oxide moiety with either unsubstituted, substituted, or isotopically labeled carbon atoms in a single laboratory operation.
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