Cytolytic T-cell granules: biochemical properties and functional specificity

The molecular mechanism of lymphocyte-mediated tumor cell lysis.

Immunology today·2014

Perforin-2 restricts growth of Chlamydia trachomatis in macrophages.

Infection and immunity·2013

Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction.

Tissue antigens·2013

CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice.

Mucosal immunology·2013

Cell-secreted Gp96-Ig-peptide complexes induce lamina propria and intraepithelial CD8+ cytotoxic T lymphocytes in the intestinal mucosa.

Mucosal immunology·2009

A critical analysis of the tumour immunosurveillance controversy for 3-MCA-induced sarcomas.

British journal of cancer·2009

Nucleoskeletal Proteins in Early Embryogenesis.

Advances in experimental medicine and biology·2026

Nuclear Dynamics and Its Timing Regulation Revealed by Live-Cell Imaging.

Advances in experimental medicine and biology·2026

Histone Modifications in Mammalian Early Embryos.

Advances in experimental medicine and biology·2026

Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.

Advances in experimental medicine and biology·2026

Asymmetric Chromosome Establishment and Segregation During Germline Stem Cell Division.

Advances in experimental medicine and biology·2026

Non-random Sister Chromatid Segregation Mediated by Ribosomal DNA in Drosophila Male Germline Stem Cells.

Advances in experimental medicine and biology·2026

Immune Circuit Rewiring by HDAC Inhibition Enables Response to Dual Checkpoint Blockade in Metastatic Breast Cancer.

Cancer research·2026

Synchronous Papillary Thyroid Carcinoma and an Angiomatoid Fibrous Histiocytoma: A Rare, Interesting Case Report.

Cureus·2026

Hyalinizing Trabecular Tumor of the Thyroid Gland: A Diagnostic and Surgical Challenge.

Cureus·2026

Neural regulation of immune evasion in breast cancer: a multiscale neuro-immune framework.

Frontiers in immunology·2026

Beyond exhaustion: T cell fitness for next generation of immunotherapy for hematological cancer.

Frontiers in immunology·2026

Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment.

Cancer cell·2026

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Cytolytic T-cell granules: biochemical properties and functional specificity

Related Concept Videos

The molecular mechanism of lymphocyte-mediated tumor cell lysis.

Perforin-2 restricts growth of Chlamydia trachomatis in macrophages.

Role of major histocompatibility complex class II expression by non-hematopoietic cells in autoimmune and inflammatory disorders: facts and fiction.

CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice.

Cell-secreted Gp96-Ig-peptide complexes induce lamina propria and intraepithelial CD8+ cytotoxic T lymphocytes in the intestinal mucosa.

A critical analysis of the tumour immunosurveillance controversy for 3-MCA-induced sarcomas.

Nucleoskeletal Proteins in Early Embryogenesis.

Nuclear Dynamics and Its Timing Regulation Revealed by Live-Cell Imaging.

Histone Modifications in Mammalian Early Embryos.

Oocyte Kinetochores at the Nexus of Meiotic Drive and Segregation Fidelity.

Asymmetric Chromosome Establishment and Segregation During Germline Stem Cell Division.

Non-random Sister Chromatid Segregation Mediated by Ribosomal DNA in Drosophila Male Germline Stem Cells.

Immune Circuit Rewiring by HDAC Inhibition Enables Response to Dual Checkpoint Blockade in Metastatic Breast Cancer.

Synchronous Papillary Thyroid Carcinoma and an Angiomatoid Fibrous Histiocytoma: A Rare, Interesting Case Report.

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