Related Experiment Video
Updated: Jun 24, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Beyond Infection: Mortality and End-of-Life Care Associated With Infectious Disease Consultation in an Academic
Alison G C Smith1, Michael E Yarrington2, Arthur W Baker2
1Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
Infectious diseases (ID) physicians increasingly consult on complex patients nearing end-of-life. This study highlights the growing need for ID specialists to integrate palliative care into their practice for improved patient outcomes.
Area of Science:
- Infectious Diseases
- Palliative Care
- Health Services Research
Background:
- Infectious diseases (ID) physicians face growing challenges managing patients with terminal illnesses and incurable infections.
- The complexity of patients requiring ID consultations has increased significantly over the past decade.
Purpose of the Study:
- To analyze trends in ID consultations over a 10-year period.
- To evaluate the characteristics and outcomes of patients receiving ID consultations, particularly those with end-of-life care needs.
- To examine the integration of palliative care services with ID consultations.
Main Methods:
- Retrospective cohort study of all inpatient ID consults within an academic health system from 2014 to 2023.
- Inclusion of community, general, and transplant ID consult services.
- Analysis of patient demographics, mortality rates, hospice discharges, and palliative care consultations.
Main Results:
- A 94% increase in ID consults was observed, rising from 5.0 to 9.9 per 100 inpatients.
- In-hospital mortality was 7.5% for patients receiving ID consults, with higher rates in transplant ID (10.7%).
- 2.6% of patients were discharged to hospice, and 7.6% received concurrent palliative care consultation, often after the ID consult.
Conclusions:
- Patients receiving ID consultations are increasingly complex and have a higher likelihood of mortality.
- ID clinicians play a crucial role in end-of-life care discussions and planning.
- There is a need to integrate palliative care principles and consultations earlier in the management of complex ID patients.
More Related Videos
Related Concept Videos
Ethical Issues
Ethical Concerns in Healthcare:
Ethical Dilemmas II
Continuing Care
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...

