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Updated: Jun 24, 2025

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Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
Published on: March 11, 2016
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Retinal image quality for multifocal lenses with on- and off-axis annular zones
1Division of Neurobiology, University of California, Berkeley, CA 94720-3200, USA.
Biomedical Optics Express
|June 13, 2024
Summary
This study explores multifocal lens design, showing that altering wavefront curvature and tilt can enhance depth of focus. Both methods proved nearly interchangeable for improving vision quality.
Area of Science:
- Ophthalmic Optics
- Visual Science
- Optical Engineering
Background:
- Multifocal intraocular and contact lenses aim to improve depth of focus.
- Conventional designs use annular zones with additional refractive power, creating specific wavefront patterns.
Purpose of the Study:
- To investigate an alternative method for influencing depth of focus in multifocal lenses.
- To compare the effects of wavefront curvature (refractive power) and wavefront tilt on retinal image quality.
Main Methods:
- Calculated retinal image light distributions for a single annulus bifocal lens using diffraction theory.
- Analyzed through-focus scans using four distinct measures of retinal image quality.
- Considered the operational characteristics of Shack-Hartmann wavefront sensors for lens testing.
Main Results:
- Both plus power additions and wavefront tilts were found to be nearly interchangeable in their effect on depth of focus.
- Wavefront tilt offers a viable alternative to traditional refractive power adjustments for modulating focal depth.
Conclusions:
- Altering wavefront tilt, in addition to refractive power, provides a flexible approach to designing multifocal ophthalmic lenses.
- Accurate characterization of lens testing equipment, such as Shack-Hartmann devices, is crucial for reliable analysis.
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