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Molecular and genetics inquiry program using Drosophila eyes absent gene
Jinhyeon Choi1, Sang-Hak Jeon2, Hyeon-Pyo Shim3
1The Center for Educational Research, Seoul National University, Seoul, Republic of Korea.
Summary
This study developed a modular molecular genetics program using the Drosophila melanogaster eyes absent gene. Students gained a contextual understanding of authentic scientific research through hands-on experiments.
Area of Science:
- Molecular genetics
- Developmental biology
- Genetics education
Background:
- Inquiry-based learning is crucial for science education.
- Molecular genetics offers complex concepts suitable for advanced middle school students.
- The eyes absent gene in Drosophila melanogaster provides a model for genetic studies.
Purpose of the Study:
- To develop and implement a modular molecular genetics inquiry program.
- To utilize the eyes absent gene of Drosophila melanogaster as a model system.
- To foster an understanding of authentic scientific research processes in students.
Main Methods:
- Program development incorporating mutation observation, cross-breeding, bioinformatics, gDNA extraction, and PCR.
- Modular design for flexible implementation.
- Implementation with gifted middle school students at a university science education institute.
Main Results:
- Students reported positive experiences with the program.
- The program successfully integrated a reasoning process aligned with scientific research.
- The modular design allowed for adaptable implementation.
Conclusions:
- The developed program effectively provides students with contextual understanding of authentic research.
- The program successfully engaged middle school students in molecular genetics inquiry.
- Recommendations are provided for effective program implementation in science education.

