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Related Concept Videos

Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

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The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
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Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

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An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
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Prospective, randomized controlled study evaluating a double-balloon interventional endoscopic platform for

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  • 1Institute for Digestive Health and Liver Diseases, Mercy Medical Center, Baltimore, Maryland, USA.

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Double-balloon interventional platform endoscopic submucosal dissection (ESD) significantly reduces colorectal polyp removal time and cost. This advanced technique improves en bloc resection rates and simplifies defect closure, making it a valuable tool for wider ESD adoption.

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Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Medical Device Technology

Background:

  • Endoscopic submucosal dissection (ESD) for colorectal polyps can be lengthy and complex.
  • A novel double-balloon interventional platform (DBIP) was developed to aid navigation, stabilization, traction, and device delivery during colorectal ESD.
  • This study prospectively compares traditional ESD (T-ESD) with DBIP-assisted ESD (DBIP-ESD).

Purpose of the Study:

  • To evaluate the efficacy and efficiency of DBIP-assisted ESD compared to traditional ESD for colorectal polyps.
  • To determine the impact of DBIP on procedure time, resection rates, cost, and adverse events.

Main Methods:

  • A prospective, randomized trial involving 140 patients with colorectal polyps ≥2 cm.
  • Patients were randomized to either DBIP-ESD or T-ESD.
  • Primary endpoint: mean total procedure time; Secondary endpoints: en bloc resection rate, cost, adverse events.

Main Results:

  • DBIP-ESD significantly reduced mean procedure time by approximately 51 minutes (P < .001) and procedural costs by $610.16 per patient.
  • Dissection speed increased by 49.0% with DBIP-ESD (P < .001).
  • En bloc resection rates were superior with DBIP-ESD (97.2% vs. 87.0%, P = .030), with no reported adverse events.

Conclusions:

  • DBIP-assisted ESD is a more efficient and cost-effective method for colorectal polyp removal.
  • The platform enhances en bloc resection rates and simplifies defect closure, promoting wider adoption of ESD.
  • DBIP represents a promising technological advancement for complex endoscopic procedures.