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Fatma Said1, Ines Naceur1, Tayssir Ben Achour1

  • 1Department of Internal Medicine, La Rabta Hospital. Tunis El Manar University, Faculty of Medicine, Tunis. Tunisia.

La Tunisie Medicale
|July 10, 2024
PubMed
Summary

Diagnosing Sjögren syndrome (SS) in older adults is challenging. While not a distinct disease subset, elderly patients with SS require closer monitoring and tailored management due to their unique vulnerabilities.

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Area of Science:

  • Rheumatology
  • Geriatrics
  • Immunology

Context:

  • Sjögren syndrome (SS) diagnosis in the elderly presents challenges due to overlapping symptoms with aging, comorbidities, and iatrogenic causes.
  • Distinguishing SS from age-related conditions is crucial for timely and appropriate patient care.

Purpose:

  • To compare the epidemiological, clinical, biological, and therapeutic characteristics of elderly patients (EP) with Sjögren syndrome (SS) against younger patients (YP).
  • To identify any distinct features or management differences in elderly individuals diagnosed with SS.

Summary:

  • A retrospective study of 323 SS patients (35 elderly) found earlier diagnosis in the elderly.
  • Fatigue was more prevalent in elderly SS patients, while anti-SSA antibodies were more common in younger patients.
  • Treatment with anti-malarial agents was less frequent in the elderly, with no significant differences in other clinical, laboratory, or outcome measures.

Impact:

  • Sjögren syndrome in the elderly appears to share core features with younger populations, suggesting it is not a separate disease entity.
  • Elderly patients with SS necessitate heightened clinical attention and individualized management strategies owing to their increased vulnerability and complex health profiles.
Keywords:
Sjögren syndromeelderly

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