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Updated: Jul 16, 2026
28:13
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
33.4K
VARIPULSE: A step-by-step guide to pulmonary vein isolation.
Devi G Nair1, Tara Gomez2, Tom De Potter3
1Electrophysiology Division, St. Bernards Healthcare, Jonesboro, Arkansas, USA.
Journal of Cardiovascular Electrophysiology
|July 15, 2024
Summary
The VARIPULSE™ variable-loop circular catheter (VLCC) system offers pulsed field ablation for atrial fibrillation treatment. This integrated system uses mapping for precise pulmonary vein isolation, potentially reducing collateral damage.
Area of Science:
- Cardiovascular Electrophysiology
- Minimally Invasive Cardiac Surgery
Background:
- The VARIPULSE™ variable-loop circular catheter (VLCC) is a bidirectional, multielectrode catheter.
- It integrates with the CARTO 3™ system for electrophysiological mapping and pulsed field energy delivery via the TRUPULSE™ Generator.
- This forms a fully integrated system for atrial fibrillation treatment.
Purpose of the Study:
- To review the step-by-step workflow for using the integrated pulsed field ablation system.
- To detail patient selection, mapping, catheter manipulation, and ablation strategies.
- To discuss initial clinical experiences, including ablation without fluoroscopy.
Main Methods:
- Pulsed field ablation (PFA) utilizes cardiac tissue-selective energy with minimal thermal effect.
- Integration with a 3D electroanatomical mapping system (CARTO 3™) allows for tracking energy density and catheter placement.
- This aims to reduce collateral tissue damage and improve system usability.
Main Results:
- The review covers patient selection, mapping, and the ablation workflow.
- It includes details on catheter repositioning, ensuring contact, and managing anatomical variations.
- Initial clinical experience with ablation without fluoroscopy is discussed.
Conclusions:
- The VLCC is part of an integrated PFA system for pulmonary vein isolation.
- Mapping guides catheter placement and lesion creation for effective treatment.
- The workflow may be refined with further real-world application of the PFA system.
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