Iodine-Promoted Sulfoximidation of Cinnamic Acids via Oxidative C═C Bond Cleavage
Parbin Rahman1, Nikita Chakraborty2, Bhisma K Patel2
1Department of Chemistry, Handique Girls' College, Guwahati 781001, Assam, India.
Abstract:
An iodine-promoted C═C bond cleavage with concomitant decarboxylation and cross-coupling between cinnamic acids and NH-sulfoximines has been developed. This reaction proceeds via selective C═C bond cleavage, followed by decarboxylation and oxidative sulfoximidation. This metal- and base-free protocol involves dioxygen as the source of oxygen, which is facilitated by tert-butyl hydroperoxide (TBHP) as the oxidant affording N-aroylated sulfoximines with good functional group tolerance and good yields.
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