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Anti-Mullerian Hormone Assessment in Assisted Reproductive Technique Outcome and Natural Conception
Inès Sellami1, Anne Laure Barbotin2,3, Valérie Bernard4,5
1Service de Médecine de la Reproduction et Préservation de la Fertilité, APHP-Université Paris-Saclay, Hôpital Antoine Béclère, Clamart, France.
Seminars in Reproductive Medicine
|July 18, 2024
Summary
Anti-Mullerian hormone (AMH) is a key indicator for predicting natural pregnancy and outcomes of assisted reproductive techniques (ART). AMH levels help manage fertility and assess ovarian reserve in women undergoing fertility treatments.
Area of Science:
- Reproductive Endocrinology
- Infertility Research
- Gynecology
Background:
- Rising infertility rates affect approximately 1 in 6 couples, necessitating assisted reproductive techniques (ART).
- Anti-Mullerian hormone (AMH), initially identified in embryonic development, plays a crucial role in folliculogenesis and ovarian reserve.
- Serum AMH assays, developed in the 1990s, are now integral to managing female fertility.
Purpose of the Study:
- To review the current understanding of Anti-Mullerian hormone (AMH) assessment in reproductive medicine.
- To evaluate the predictive value of AMH levels for spontaneous pregnancy.
- To analyze the role of AMH in predicting outcomes of assisted reproductive techniques (ART) and fertility preservation.
Main Methods:
- Literature review of studies on Anti-Mullerian hormone (AMH) in reproductive medicine.
- Analysis of AMH assay utility in predicting fertility outcomes.
- Focus on AMH's role in spontaneous conception, ART success rates, and fertility preservation.
Main Results:
- Serum AMH levels serve as a quantitative marker of ovarian reserve.
- AMH is widely utilized in managing women's fertility and guiding ART protocols.
- The hormone's predictive capacity for spontaneous pregnancy, ART outcomes, and fertility preservation is established.
Conclusions:
- Anti-Mullerian hormone (AMH) assessment is a vital tool in modern reproductive medicine.
- AMH levels provide crucial insights into a woman's reproductive potential.
- This review consolidates knowledge on AMH's application in fertility management and treatment success prediction.

