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Resolving Atomic-Level Dynamics and Interactions of High-Molecular-Weight Hyaluronic Acid by Multidimensional

Pushpa Rampratap1, Alessia Lasorsa1, Abinaya Arunachalam1

  • 1Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, Groningen 9747 AG, The Netherlands.

ACS Applied Materials & Interfaces
|August 9, 2024
PubMed
Summary

High-molecular-weight hyaluronic acid (HA) conformations and dynamics were revealed using advanced NMR spectroscopy. This study uncovers how HA interacts with the extracellular matrix, offering insights into tumor biology and biomaterials.

Keywords:
dynamicsextracellular matrixhigh-molecular-weight hyaluronic acidhydrogelspolysaccharidessolid-state NMR

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