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Office-Based Blue Laser Therapy vs Thulium Laser Therapy for Reinke's Edema
Abdul-Latif Hamdan1, Jad Hosri1, Christophe Abi Zeid Daou1
1Department of Otolaryngology-Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Journal of Voice : Official Journal of the Voice Foundation
|August 10, 2024
Summary
Blue laser and thulium laser treatments for Reinke's edema (RE) show similar outcomes in voice improvement and lesion regression. Both lasers are effective for in-office RE treatment, with no significant differences observed between them.
Area of Science:
- Otolaryngology
- Laser Surgery
- Voice Disorders
Background:
- Reinke's edema (RE) is a condition affecting vocal cords, often treated with surgical interventions.
- Office-based laser treatments offer a less invasive approach for managing RE.
Purpose of the Study:
- To compare the efficacy of in-office blue laser therapy versus thulium laser therapy for Reinke's edema.
- To evaluate treatment outcomes based on voice quality and laryngeal examination findings.
Main Methods:
- A retrospective case-control study reviewed 22 patients with RE treated with either blue laser or thulium laser in-office.
- Outcomes were assessed using the Voice Handicap Index-10 (VHI-10) and laryngeal examination for disease regression.
Main Results:
- No significant difference was found in the mean VHI-10 score reduction between blue laser (8.2 ± 5.98) and thulium laser (10.5 ± 13.15) groups.
- Complete disease regression rates were comparable: 52.9% for blue laser and 40.9% for thulium laser, with no statistical significance.
Conclusions:
- Both blue laser and thulium laser are effective and interchangeable for in-office treatment of Reinke's edema.
- Further research with objective measures is recommended to validate these findings.

