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Updated: Jul 9, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Self-Perceived Hoarseness and Voice Disorders in E-cigarette and Conventional Cigarette Users
Abdul-Latif Hamdan1, Elie Alam1, Marc Mourad1
1Department of Otolaryngology-Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
E-cigarette users with hoarseness reported less voice handicap than traditional smokers, but more than non-smokers. E-cigarettes impact voice quality and vocal folds, affecting quality of life.
Area of Science:
- Otolaryngology
- Public Health
- Respiratory Medicine
Background:
- E-cigarettes (vaping) are increasingly popular across all age groups, especially adolescents and young adults.
- Research suggests vaping negatively impacts the phonatory system, leading to voice disorders.
- Hoarseness is a common symptom linked to smoking, including e-cigarette use.
Purpose of the Study:
- To assess self-perceived voice handicap in e-cigarette users with hoarseness.
- To identify voice disorders in e-cigarette users.
- To compare these outcomes with traditional cigarette smokers.
Main Methods:
- A comparative study included e-cigarette smokers, traditional cigarette smokers, and non-smokers presenting with hoarseness.
- Participants were matched for age and gender.
- Data collected: smoking type, allergies, reflux, Voice Handicap Index-10 (VHI-10), and voice disorder types.
Main Results:
- E-cigarette smokers had a higher mean VHI-10 score (7.04) than non-smokers (3.92) but lower than traditional smokers (12.68).
- 28% of e-cigarette smokers reported VHI-10 scores ≥11, versus 60% of traditional smokers and 16% of non-smokers.
- No significant difference in voice disorder types or vocal fold pathology was found between e-cigarette and traditional smokers.
Conclusions:
- E-cigarette users with hoarseness experience less voice handicap impacting quality of life than traditional smokers.
- However, e-cigarette use is associated with more severe voice handicap and vocal fold pathology compared to non-smokers.
- Vaping poses risks to voice quality and vocal fold health, affecting users' quality of life.
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