Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.7K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.7K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

206
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
206
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

427
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
427
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

160
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
160
Disorders of Hemostasis01:24

Disorders of Hemostasis

758
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
758
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

290
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
290

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnosis and management of yellow nail syndrome: An international multi-institutional retrospective cohort study of 111 cases by an expert panel.

Journal of the American Academy of Dermatology·2025
Same author

Evaluation and diagnosis of longitudinal melanonychia: A clinical review by a nail expert group.

Journal of the American Academy of Dermatology·2025
Same author

Nail toxicity associated with anticancer agents.

Journal of the American Academy of Dermatology·2025
Same author

Curly fingernails as a potential new nail variant: A report of two cases.

JAAD case reports·2024
Same author

Congenital ichthyosis is associated with cutaneous infections in a case-control study of 2260 patients.

Clinical and experimental dermatology·2024
Same author

Optimizing Patient Care With Teledermatology: Improving Access, Efficiency, and Satisfaction.

Cutis·2024
Same journal

Black Dots on the Scalp of a Child.

Cutis·2026
Same journal

Psoriasis and Obesity: A Clinical Review of the Bidirectional Link and Management Implications.

Cutis·2026
Same journal

Adalimumab in Lichen Planus: A Narrative Review of Treatment and Paradoxical Reactions.

Cutis·2026
Same journal

The Future of Psoriasis Care.

Cutis·2026
Same journal

Evaluating GPT-4o for Automated Classification of Skin Lesions Using the HAM10000 Dataset.

Cutis·2026
Same journal

Metastatic Primary Extramammary Paget Disease: A Case Series.

Cutis·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2025

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.4K

Tackling Inflammatory and Infectious Nail Disorders in Children.

Eden N Axler1, Jane S Bellet1, Shari R Lipner1

  • 1Eden N. Axler and Dr. Lipner are from the Israel Englander Department of Dermatology, Weill Cornell Medicine, New York, New York. Dr. Bellet is from the Department of Dermatology and the Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.

Cutis
|August 19, 2024
PubMed
Summary
This summary is machine-generated.

Pediatric nail disorders, including inflammatory and infectious types, are common and impact children's quality of life. Early recognition of distinct features aids dermatologists in diagnosis and management.

More Related Videos

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

17.1K
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.4K

Related Experiment Videos

Last Updated: Jun 16, 2025

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.4K
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

17.1K
Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.4K

Area of Science:

  • Pediatric Dermatology
  • Nail Disorders
  • Clinical Review

Background:

  • Nail conditions are prevalent in children, significantly affecting their quality of life.
  • These disorders encompass both inflammatory and infectious etiologies.
  • They can manifest with or without concurrent skin involvement.

Purpose of the Study:

  • To review common inflammatory and infectious nail disorders in pediatric patients.
  • To highlight distinctive clinical features and presentations.
  • To enhance dermatologist awareness for improved diagnosis and management.

Main Methods:

  • Literature review of inflammatory nail conditions: nail psoriasis, nail lichen planus (NLP), trachyonychia, nail lichen striatus, nail atopic dermatitis (AD).
  • Literature review of infectious nail conditions: nail disease associated with hand, foot, and mouth disease (HFMD) or Kawasaki disease, onychomycosis, acute paronychia.
  • Analysis of distinctive features and clinical presentations.

Main Results:

  • Identified key inflammatory nail disorders including nail psoriasis, NLP, trachyonychia, nail lichen striatus, and AD.
  • Identified key infectious nail disorders including HFMD-related, Kawasaki disease-related, onychomycosis, and acute paronychia.
  • Differentiated presentations based on etiology and involvement.

Conclusions:

  • Inflammatory and infectious nail disorders present unique challenges in pediatric dermatology.
  • Understanding specific clinical features is crucial for accurate diagnosis.
  • Increased dermatologist awareness can lead to better patient outcomes.