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Contrast-free visualization of distal trigeminal nerve segments using MR neurography
Sulagna Sahu1, Dane Hellwig2, Zachary Morrison3
1School of Biological and Health System Engineering, Arizona State University, Tempe, Arizona, USA.
Summary
A combined 3-dimensional cranial nerve imaging (CRANI) and MPRAGE protocol effectively visualizes trigeminal nerve branches. This imaging approach shows potential for clinical diagnosis and surgical planning.
Area of Science:
- Medical Imaging
- Neuroimaging
- Radiology
Background:
- 3-dimensional cranial nerve imaging (CRANI) aids visualization of extraforaminal cranial nerves.
- Accurate imaging is crucial for clinical diagnosis and preoperative planning.
Purpose of the Study:
- To assess the feasibility of a combined CRANI and magnetization-prepared rapid-acquisition gradient-echo (MPRAGE) protocol.
- To comprehensively identify trigeminal nerve projections using this combined protocol.
Main Methods:
- Evaluated detection of V1, V2, and V3 nerve branches in seven healthy adults.
- Used a combined CRANI and MPRAGE protocol with and without contrast.
- Assessed nerve branch visualization using a 5-point scale and interobserver reliability.
Main Results:
- Frontal and infraorbital nerves (V1, V2) best visualized with precontrast MPRAGE.
- Lingual and inferior alveolar nerves (V3) best visualized with precontrast CRANI.
- Gadolinium contrast did not enhance visualization; interobserver reliability was good to excellent for most branches.
Conclusions:
- A combined CRANI and MPRAGE protocol can visualize distal trigeminal nerve branches (V1, V2, V3).
- This protocol demonstrates potential for clinical application in diagnosis and surgical planning.
