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Related Experiment Video

Updated: Jun 14, 2025

Author Spotlight: Fu's Subcutaneous Needling for Knee Osteoarthritis Pain
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9. Chronic knee pain.

Thibaut Vanneste1,2,3, Amy Belba1,2,4, Gezina T M L Oei5,6

  • 1Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Multidisciplinary Pain Center, Genk, Belgium.

Pain Practice : the Official Journal of World Institute of Pain
|September 2, 2024
PubMed
Summary
This summary is machine-generated.

For chronic knee pain unresponsive to conservative care, a multidisciplinary approach is recommended. This includes psychological therapy, integrative treatments, and procedures like injections and radiofrequency ablation for osteoarthritis (OA) of the knee.

Keywords:
chronic knee paincorticosteroidsgenicular nerveshyaluronic acidosteoarthritisradiofrequency treatmentspinal cord stimulation

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Area of Science:

  • Orthopedics
  • Pain Management
  • Rheumatology

Background:

  • Chronic knee pain, persisting over three months, is often caused by degenerative osteoarthritis (OA).
  • Osteoarthritis of the knee presents with insidious, progressively worsening pain, primarily nociceptive.
  • Accurate diagnosis requires a thorough examination, potentially supplemented by imaging, to differentiate from other knee pathologies.

Purpose of the Study:

  • To provide a comprehensive overview of knee osteoarthritis (OA) pathology, diagnosis, and treatment.
  • To formulate evidence-based recommendations for interventional treatments for chronic knee pain.

Main Methods:

  • Literature review on knee pain diagnosis and treatment.
  • Modified Delphi approach for interventional treatment recommendations.

Main Results:

  • Knee OA pain is predominantly nociceptive, with occasional nociplastic and neuropathic components.
  • Conservative treatment failure may warrant intra-articular corticosteroids or genicular nerve radiofrequency ablation.
  • Hyaluronic acid injections are conditionally recommended; PRP, nerve ablation, and neurostimulation lack sufficient evidence.

Conclusions:

  • A multidisciplinary approach is advised when conservative measures for knee OA fail.
  • Integrative treatments, psychological therapy, and procedural options are key components of advanced management.
  • Procedural options include intra-articular injections, radiofrequency ablation, and surgical interventions, requiring multidisciplinary decision-making.